Article
Chromosome togetherness at the onset of ESC differentiation.
Cell stem cell - 5 Mar 2015
Krivega Ivan, Dean Ann
Abstract excerpt
Pairing of homologous alleles is a phenomenon generally associated with imprinted and mono-allelically expressed loci. In this issue, Hogan et al. (2015) examine the earliest steps between pluripotency and lineage commitment in ESCs and find a critical role for transient pairing of Oct4 alleles in exiting the pluripotent state.
Read the complete abstract on PubMedTopics
Share this publication in a Topic to start or enrich a Post.
