Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

A candidate gene study of one-carbon metabolism pathway genes and colorectal cancer risk.

The British journal of nutrition - 28 Mar 2013

Martinelli Marcella, Scapoli Luca, Mattei Gabriella, Ugolini Giampaolo, Montroni Isacco, Zattoni Davide, Rosati Giancarlo, Solmi Rossella

Abstract excerpt

The risk of colorectal cancer (CRC) may be influenced by aberrant DNA methylation and altered nucleotide synthesis and repair, possibly caused by impaired dietary folate intake as well as by polymorphic variants in one-carbon metabolism genes. A case-control study using seventy-one CRC patients and eighty unrelated healthy controls was carried out to assess the genetic association of fifteen SNP and one insertion...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Carbon
Share to Diet

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to Folic Acid

Share to Methionine

Share to Mutagenesis, Insertional

Share to Nucleotides

Share to Transcobalamins

Share to Vitamin B 12

Source

Identifiers

PMID: 22794911
DOI: 10.1017/S0007114512002796

Genes

TCN2

Variants

rs1801198

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

A candidate gene study of one-carbon metabolism pathway genes and colorectal cancer risk.PMID 22794911Read ↗

Twenty-four non-synonymous polymorphisms in the one-carbon metabolic pathway and risk of colorectal adenoma in the Nurses' Health Study.Semantic proximity Read ↗

Nonsynonymous polymorphisms in genes in the one-carbon metabolism pathway and associations with colorectal cancer.Semantic proximity Read ↗

A candidate gene study of folate-associated one carbon metabolism genes and colorectal cancer risk.Semantic proximity Read ↗

Folate-mediated one-carbon metabolism genes and interactions with nutritional factors on colorectal cancer risk: Women's Health Initiative Observational Study.Semantic proximity Read ↗

One-carbon genetic variants and the role of MTHFD1 1958G>A in liver and colon cancer risk according to global DNA methylation.Semantic proximity Read ↗

Investigation of inter-individual variability of the one-carbon folate pathway: a bioinformatic and genetic review.Semantic proximity Read ↗

One-carbon metabolism biomarkers and genetic variants in relation to colorectal cancer risk by KRAS and BRAF mutation status.Semantic proximity Read ↗

Genetic polymorphisms in the one-carbon metabolism pathway and breast cancer risk: a population-based case-control study and meta-analyses.Semantic proximity Read ↗

Polymorphisms of one-carbon-metabolizing genes and risk of breast cancer in a population-based study.Semantic proximity Read ↗

Pathway analysis of genetic variants in folate‐mediated one‐carbon metabolism‐related genes and survival in a prospectively followed cohort of colorectal cancer patientsSemantic proximity Read ↗

Large-scale population-based metabolic phenotyping of thirteen genetic polymorphisms related to one-carbon metabolism.Semantic proximity Read ↗

One-carbon metabolism related gene polymorphisms interact with alcohol drinking to influence the risk of colorectal cancer in Japan.Semantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.