Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Gastrointestinal Adenocarcinomas of the Esophagus, Stomach, and Colon Exhibit Distinct Patterns of Genome Instability and Oncogenesis

3 Jul 2012

Abstract excerpt

A more detailed understanding of the somatic genetic events that drive gastrointestinal adenocarcinomas is necessary to improve diagnosis and therapy. Using data from high-density genomic profiling arrays, we conducted an analysis of somatic copy-number aberrations in 486 gastrointestinal adenocarcinomas including 296 esophageal and gastric cancers. Focal amplifications were substantially more prevalent in...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Cancer Genomics and Diagnostics
Share to Gastrointestinal Tumor Research and Treatment
Share to Pancreatic and Hepatic Oncology Research

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Source

Identifiers

PMID: 22751462
DOI: 10.1158/0008-5472.can-11-3893

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Gastrointestinal Adenocarcinomas of the Esophagus, Stomach, and Colon Exhibit Distinct Patterns of Genome Instability and OncogenesisPMID 22751462Read ↗

A comprehensive survey of genomic alterations in gastric cancer reveals systematic patterns of molecular exclusivity and co-occurrence among distinct therapeutic targets.Semantic proximity Read ↗

Genomics and Targeted Therapies in Gastroesophageal AdenocarcinomaSemantic proximity Read ↗

Genome-wide analysis of esophageal adenocarcinoma yields specific copy number aberrations that correlate with prognosis.Semantic proximity Read ↗

Comprehensive Genomic Profiling of Advanced Esophageal Squamous Cell Carcinomas and Esophageal Adenocarcinomas Reveals Similarities and Differences.Semantic proximity Read ↗

Unearthed Novel Molecular Phenotypes and Potential Therapeutic Targets in Esophagogastric AdenocarcinomaSemantic proximity Read ↗

Common and distinct genomic events in sporadic colorectal cancer and diverse cancer types.Semantic proximity Read ↗

Comparative Molecular Analysis of Gastrointestinal Adenocarcinomas.Semantic proximity Read ↗

Genomic characterization reveals distinct mutation landscapes and therapeutic implications in neuroendocrine carcinomas of the gastrointestinal tract.Semantic proximity Read ↗

Prospective comprehensive genomic profiling of advanced gastric carcinoma cases reveals frequent clinically relevant genomic alterations and new routes for targeted therapies.Semantic proximity Read ↗

Next-Generation Sequencing of 487 Esophageal Adenocarcinomas Reveals Independently Prognostic Genomic Driver Alterations and Pathways.Semantic proximity Read ↗

A molecular portrait of gastrointestinal stromal tumors: an integrative analysis of gene expression profiling and high-resolution genomic copy number.Semantic proximity Read ↗

The genomic landscape of oesophagogastric junctional adenocarcinoma.Semantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.