Article
Differences in the susceptibility to iodine¹³¹-induced thyroid tumours amongst inbred mouse strains.
Journal of radiation research - 1 Jan 2012
Dalke Claudia, Hölzlwimmer Gabriele, Calzada-Wack Julia, Quintanilla-Martinez Leticia, Atkinson Michael J, Rosemann Michael
Abstract excerpt
Genetic factors can modify susceptibility to the carcinogenic effect of ionising radiation. To establish if radioiodine-induced thyroid cancer is similarly genetically influenced, we studied F1 hybrid crosses between inbred mouse strains. Mice were perinatally exposed to iodine-131 and thyroid tissues examined after 18 months. Differences in the incidence and distribution of histological subtypes were quantified...
Read the complete abstract on PubMedTopics
Share this publication in a Topic to start or enrich a Post.
