Article
Parental bias of Ki-ras oncogenes detected in lung tumors from mouse hybrids.
Proceedings of the National Academy of Sciences of the United States of America - 1 Jul 1992
You M, Wang Y, Stoner G, You L, Maronpot R, Reynolds S H, Anderson M
Abstract excerpt
A mouse strain with low lung tumor susceptibility (C3H) and a strain with high lung tumor susceptibility (A/J) were reciprocally crossed to produce C3A and AC3 F1 hybrid mice. Ki-ras oncogenes were detected in spontaneous and chemically induced lung tumors obtained from the C3A and AC3 mice. To further explore the genetics of the Ki-ras gene in mouse lung tumor susceptibility, the parental origin of Ki-ras...
Topics
- 3T3 Cells
- Animals
- Base Sequence
- DNA, Neoplasm
- Genes, ras
- Lung Neoplasms
- Mice
- Mice, Inbred A
- Mice, Inbred C3H
- Molecular Sequence Data
- Mutation