MHC and non-MHC genes in lung tumor susceptibility in the mouse: implications for the study of the different lung tumor types and their cell of origin.

doi:10.3109/01902149109064419

Back to search

Article

MHC and non-MHC genes in lung tumor susceptibility in the mouse: implications for the study of the different lung tumor types and their cell of origin.

Experimental lung research - 1 Jan 2000

Oomen L C, van der Valk M A, Demant P

Abstract excerpt

Lung tumorigenesis in the mouse is controlled by multiple genes, which until now largely escaped detection because of the limitations of the available genetic tools. Therefore, we have developed the Recombinant Congenic Strains (RCS), which can be used to separate and map individual tumor suscept...

Topics

Animals
Ethylnitrosourea
Genetic Predisposition to Disease
Lung Neoplasms
Major Histocompatibility Complex
Mice
Pulmonary Alveoli

Community interpretation

Discuss the evidence

Ask a question, add context or challenge an interpretation. Community activity is separate from scientific evidence strength.

discussions

replies

Citations encouraged

Claims remain attributable.

No discussion yet

Be the first to add a careful, cited interpretation.