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Article

Predisposition to mouse thymic lymphomas in response to ionizing radiation depends on variant alleles encoding metal-responsive transcription factor-1 (Mtf-1).

Oncogene - 13 Jan 2005

Tamura Yasushi, Maruyama Masaki, Mishima Yukio, Fujisawa Hiromi, Obata Miki, Kodama Yasumitsu, Yoshikai Yoshihiro, Aoyagi Yutaka, Niwa Ohtsura, Schaffner Walter, Kominami Ryo

Abstract excerpt

Genetic predisposition to cancers is significant to public health because a high proportion of cancers probably arise in a susceptible human subpopulation. Using a mouse model of gamma-ray-induced thymic lymphomas, we performed linkage analysis and haplotype mapping that suggested Mtf-1, metal-responsive transcription factor-1 (Mtf-1), as a candidate lymphoma susceptibility gene. Sequence analysis revealed a...

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Identifiers

PMID: 15516976
DOI: 10.1038/sj.onc.1208197

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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