Strain-dependent differences in susceptibility to lung cancer in inbred mice exposed to mainstream cigarette smoke.

Abstract excerpt

It is becoming increasingly clear that genetic susceptibility is an important host factor determining the effects of exposure to a number of airborne particles and gases. Although numerous studies have identified a genetic component for spontaneous pulmonary tumor development and for chemically induced lung cancer (e.g., urethane) in mice, a systematic examination of murine inter-strain differences in response to...

Topics

Share this publication in a Topic to start or enrich a Post.

• Share to Genetic Predisposition to Disease
• Share to Lung Neoplasms
• Share to Mice