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Article

PCSK1 rs6232 is associated with childhood and adult class III obesity in the Mexican population.

PloS one - 1 Jan 2012

Villalobos-Comparán Marisela, Villamil-Ramírez Hugo, Villarreal-Molina Teresa, Larrieta-Carrasco Elena, León-Mimila Paola, Romero-Hidalgo Sandra, Jacobo-Albavera Leonor, Liceaga-Fuentes Adriana E, Campos-Pérez Francisco J, López-Contreras Blanca E, Tusié-Luna Teresa, Del Río-Navarro Blanca E, Aguilar-Salinas Carlos A, Canizales-Quinteros Samuel

Abstract excerpt

BACKGROUND: Common variants rs6232 and rs6235 in the PCSK1 gene have been associated with obesity in European populations. We aimed to evaluate the contribution of these variants to obesity and related traits in Mexican children and adults. METHODOLOGY/PRINCIPAL FINDINGS: Rs6232 and rs6235 were genotyped in 2382 individuals, 1206 children and 1176 adults. Minor allele frequencies were 0.78% for rs6232 and 19.99%...

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Share to Aged, 80 and over
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Source

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Identifiers

PMID: 22737226
DOI: 10.1371/journal.pone.0039037
PMCID: PMC3380862

Genes

PCSK1

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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