Contribution of common PCSK1 genetic variants to obesity in 8,359 subjects from multi-ethnic American population.

doi:10.1371/journal.pone.0057857

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Community

Back to search

Article

Contribution of common PCSK1 genetic variants to obesity in 8,359 subjects from multi-ethnic American population.

PloS one - 1 Jan 2013

Choquet Hélène, Kasberger Jay, Hamidovic Ajna, Jorgenson Eric

Abstract excerpt

Common PCSK1 variants (notably rs6232 and rs6235) have been shown to be associated with obesity in European, Asian and Mexican populations. To determine whether common PCSK1 variants contribute to obesity in American population, we conducted association analyses in 8,359 subjects using two multi-...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Black or African American

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to Case-Control Studies

Share to Follow-Up Studies

Share to Genotype

Share to Obesity

Share to Polymorphism, Single Nucleotide

Share to Proprotein Convertase 1

Share to White People

Source

Open in PubMed Open full text

Identifiers

PMID: 23451278
DOI: 10.1371/journal.pone.0057857
PMCID: PMC3581482

Genes

PCSK1

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 4 Sept 2026. Prepared record publication-23451278-2026-09-04.2. Manifest publication-graph-cohort-2026-09-04.2.

Source receipt: PubMed via Helena Literature Corpus, retrieved 4 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Contribution of common PCSK1 genetic variants to obesity in 8,359 subjects from multi-ethnic American population.PMID 23451278Read ↗

Contribution of common non-synonymous variants in PCSK1 to body mass index variation and risk of obesity: a systematic review and meta-analysis with evidence from up to 331 175 individuals.Semantic proximity Read ↗

Association of PCSK1 rs6234 with obesity and related traits in a Chinese Han population.Semantic proximity Read ↗

Association of variants in the PCSK1 gene with obesity in the EPIC-Norfolk study.Semantic proximity Read ↗

PCSK1 rs6232 is associated with childhood and adult class III obesity in the Mexican population.Semantic proximity Read ↗

The association of common variants in PCSK1 with obesity: a HuGE review and meta-analysis.Semantic proximity Read ↗

Common nonsynonymous variants in PCSK1 confer risk of obesity.Semantic proximity Read ↗

Association of the rs6235 variant in the proprotein convertase subtilisin/kexin type 1 (PCSK1) gene with obesity and related traits in a Taiwanese population.Semantic proximity Read ↗

Effects of PCSK1 genetic variants on obesity among Thai children and their family members: in relation to health risk, and biochemical and anthropometric parameters.Semantic proximity Read ↗

Common variants in PCSK1 influence blood pressure and body mass index.Semantic proximity Read ↗

Common PCSK1 haplotypes are associated with obesity in the Chinese population.Semantic proximity Read ↗

Contribution of heterozygous PCSK1 variants to obesity and implications for precision medicine: a case-control studySemantic proximity Read ↗

The effect of PCSK1 variants on waist, waist-hip ratio and glucose metabolism is modified by sex and glucose tolerance status.Semantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.