Article
Association of PCSK1 rs6234 with obesity and related traits in a Chinese Han population.
PloS one - 17 May 2010
Qi Qibin, Li Huaixing, Loos Ruth J F, Liu Chen, Hu Frank B, Wu Hongyu, Yu Zhijie, Lin Xu
Abstract excerpt
BACKGROUND: Common variants in PCSK1 have been reported to be associated with obesity in populations of European origin. We aimed to replicate this association in Chinese. METHODOLOGY/PRINCIPAL FINDINGS: Two PCSK1 variants rs6234 and rs6235 (in strong LD with each other, r(2) = 0.98) were genotyped in a population-based cohort of 3,210 Chinese Hans. The rs6234 was used for further association analyses with...
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