Article
Association of variants in the PCSK1 gene with obesity in the EPIC-Norfolk study.
Human molecular genetics - 15 Sept 2009
Kilpeläinen Tuomas O, Bingham Sheila A, Khaw Kay-Tee, Wareham Nicholas J, Loos Ruth J F
Abstract excerpt
Recently, the rs6232 (N221D) and rs6235 (S690T) SNPs in the PCSK1 gene were associated with obesity in a meta-analysis comprising more than 13 000 individuals of European ancestry. Each additional minor allele of rs6232 or rs6235 was associated with a 1.34- or 1.22-fold increase in the risk of ob...
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