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Article

The effect of PCSK1 variants on waist, waist-hip ratio and glucose metabolism is modified by sex and glucose tolerance status.

PloS one - 1 Jan 2011

Gjesing Anette P, Vestmar Marie A, Jørgensen Torben, Heni Martin, Holst Jens J, Witte Daniel R, Hansen Torben, Pedersen Oluf

Abstract excerpt

BACKGROUND: We aimed to evaluate the effects of the G-allele of rs6232 and the C-allele of rs6235 within PCSK1 on measures of body fat and glucose homeostasis in Danish individuals and to assess interactions of genotypes with age, sex and glucose tolerance status. Data were included in meta-analyses of additional Europeans. METHODOLOGY/PRINCIPAL FINDINGS: Rs6232 and rs6235 were genotyped in 6,164 Danes from the...

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Share to Adipose Tissue
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Share to Gene Expression Regulation, Enzymologic
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Source

Open in PubMed Open full text

Identifiers

PMID: 21935364
DOI: 10.1371/journal.pone.0023907
PMCID: PMC3173365

Genes

PCSK1
GIP

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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