Article
Differential sex-association between PCSK1 polymorphisms and obesity risk in Portuguese children.
American journal of human biology : the official journal of the Human Biology Council - 1 May 2024
Manco Licínio, Albuquerque David, Aranda Beatriz, Rodrigues Daniela, Machado-Rodrigues Aristides M, Padez Cristina
Abstract excerpt
OBJECTIVES: The proprotein convertase subtilisin/Kexin type 1 gene (PCSK1) is implicated in hypothalamic appetite control. Several studies have addressed the relationship between PCSK1 polymorphisms and obesity, although conflicting results were observed. We tested the potential association of four PCSK1 variants with the risk of overweight/obesity and related variables in Portuguese children. METHODS: This is a...
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