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Article

A high-throughput next-generation sequencing-based method for detecting the mutational fingerprint of carcinogens.

Nucleic acids research - 1 Aug 2012

Besaratinia Ahmad, Li Haiqing, Yoon Jae-In, Zheng Albert, Gao Hanlin, Tommasi Stella

Abstract excerpt

Many carcinogens leave a unique mutational fingerprint in the human genome. These mutational fingerprints manifest as specific types of mutations often clustering at certain genomic loci in tumor genomes from carcinogen-exposed individuals. To develop a high-throughput method for detecting the mutational fingerprint of carcinogens, we have devised a cost-, time- and labor-effective strategy, in which the widely...

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Source

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Identifiers

PMID: 22735701
DOI: 10.1093/nar/gks610
PMCID: PMC3424585

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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