Article
Mutational epidemiology: achievements and expectations on enhancing our understanding of the causes of cancer.
Journal of the National Cancer Institute. Monographs - 1 Apr 2026
Perdomo Sandra, de Carvalho Ana Carolina, Ferreiro-Iglesias Aida, Ribeiro Pinto Luis Felipe, Shibata Tatsuhiro, Brennan Paul
Abstract excerpt
Mutational epidemiology integrates genomic techniques with large-scale population studies to uncover new causes of cancer. This approach goes beyond traditional epidemiology by analyzing the patterns of somatic mutations in cancer cells to identify specific mutational signatures that serve as a historical record of an individual's past mutagenic exposures. The field is also expanding to study mutational...
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