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Article

Significance of HLA in the development of Graves' orbitopathy.

Genes and immunity - 1 Feb 2023

Stasiak Magdalena, Zawadzka-Starczewska Katarzyna, Tymoniuk Bogusław, Stasiak Bartłomiej, Lewiński Andrzej

Abstract excerpt

Graves' disease (GD), similarly to most autoimmune disease, is triggered by environmental factors in genetically predisposed individuals. Particular HLA alleles increase or decrease GD risk. No such correlation was demonstrated for Graves' orbitopathy (GO) in Caucasian population. HLA-A, -B, -C, -DQB1 and -DRB1 genotyping was performed using a high-resolution method in a total number of 2378 persons including 70...

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Share to Alleles
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Methodology Data sources Editorial policy Privacy Delete account & data About Contact Helena Bioinformatics

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Source

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Identifiers

PMID: 36639701
DOI: 10.1038/s41435-023-00193-z
PMCID: PMC9935388

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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Semantic proximity does not establish scientific evidence. Graph snapshot: 2026-09-29.

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