The clinical value of human leukocyte antigen HLA-DRB1 subtypes associated to Graves' disease in Romanian population.

doi:10.3109/08820139.2014.886261

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Article

The clinical value of human leukocyte antigen HLA-DRB1 subtypes associated to Graves' disease in Romanian population.

Immunological investigations - 1 Jan 2014

Martin Sorina, Dutescu Monica Irina, Sirbu Anca, Barbu Carmen, Albu Alice, Florea Suzana, Fica Simona

Abstract excerpt

The aim of this study was to identify the primary susceptibility HLA-DRB1 alleles associated with GD in Romanian population and to seek whether specific HLA-DRB1 haplotypes are associated with differences in the clinical presentation of GD at diagnosis. Molecular typing of HLA-DRB1 alleles was performed in 77 Romanian Caucasian GD patients and 445 racially matched controls. In GD patients, age, presence of eye...

Topics

Adult
Aged
Alleles
Case-Control Studies
Female
Gene Frequency
Genetic Predisposition to Disease
Graves Disease
HLA-DRB1 Chains
Humans
Male

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Middle Aged

Odds Ratio

Romania

Severity of Illness Index

White People

Young Adult

Source

Open in PubMed

Identifiers

PMID: 24661105
DOI: 10.3109/08820139.2014.886261

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