Article
Association of Human Leukocyte Antigens Class I and II with Graves' Disease in Iranian Population.
Iranian journal of immunology : IJI - 1 Sept 2017
Mehraji Zahra, Farazmand Ali, Esteghamati Alireza, Noshad Sina, Sadr Maryam, Amirzargar Somayeh, Yekaninejad Mir Saeed, Amirzargar Aliakbar
Abstract excerpt
BACKGROUND: Graves' disease (GD), a highly rampant autoimmune disorder of the thyroid gland, is responsible for 60-80% of the clinical cases of hyperthyroidism. Over the past decades, genetic association studies have identified several GD susceptibility loci in CTLA-4, TSHR and major histocompatibility complex regions. The information on the association between the human leukocyte antigens (HLA) and GD among...
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