Association Between HLA-DRB1 Alleles and Graves' Disease in Asian Populations: A Meta-Analysis.

doi:10.1055/a-2298-4366

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Article

Association Between HLA-DRB1 Alleles and Graves' Disease in Asian Populations: A Meta-Analysis.

Hormone and metabolic research = Hormon- und Stoffwechselforschung = Hormones et metabolisme - 1 Dec 2024

Li Wenyi, Ke Tingyu, Wang Jia, Zhu Fangling, Chi Yan

Abstract excerpt

Graves' disease (GD) is an autoimmune disease that primarily affects the thyroid gland. It is the most common cause of hyperthyroidism. Genetic studies have shown that human leukocyte antigen (HLA) plays an important role in the development of GD. In this article, we performed a meta-analysis determined to evaluate the relationship between HLA-DRB1 alleles and GD. This meta-analysis included 9 studies (3582 cases...

Topics

Humans
Alleles
Asian People
Gene Frequency
Genetic Association Studies
Genetic Predisposition to Disease
Graves Disease
HLA-DRB1 Chains

Source

Open in PubMed

Identifiers

PMID: 38698581
DOI: 10.1055/a-2298-4366

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 30 Aug 2026.

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