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Identification of HLA-DRB1 alleles associated with Graves' disease in Koreans by sequence-based typing.

Immunological investigations - 1 Jan 2011

Jang Hye Won, Shin Hyun Won, Cho Hyun-Jung, Kim Hee Kyung, Lee Ji In, Kim Sun Wook, Kim Jong-Won, Chung Jae Hoon

Abstract excerpt

The human leukocyte antigen (HLA) region, particularly class II genes, plays a primary role in the susceptibility to development of GD. We investigated the allelic polymorphism of HLA class II DRB1 genes to examine its association with GD in Koreans. We performed the high resolution polymerase chain reaction-sequence based typing (PCR-SBT) of HLA-DRB1 in 133 patients with GD and 200 healthy controls. Compared to...

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Identifiers

PMID: 21062236
DOI: 10.3109/08820139.2010.525571

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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