Article
Analysis of the association between CD40 and CD40 ligand polymorphisms and systemic sclerosis.
Arthritis research & therapy - 25 Jun 2012
Teruel María, Simeon Carmen P, Broen Jasper, Vonk Madelon C, Carreira Patricia, Camps Maria Teresa, García-Portales Rosa, Delgado-Frías Esmeralda, Gallego Maria, Espinosa Gerard, Beretta Lorenzo, Airó Paolo, Lunardi Claudio, Riemekasten Gabriela, Witte Torsten, Krieg Thomas, Kreuter Alexander, Distler Jörg H W, Hunzelmann Nicolas, Koeleman Bobby P, Voskuyl Alexandre E, Schuerwegh Annemie J, González-Gay Miguel Angel, Radstake Timothy R D J, Martin Javier
Abstract excerpt
INTRODUCTION: The aim of the present study was to investigate the possible role of CD40 and CD40 ligand (CD40LG) genes in the susceptibility and phenotype expression of systemic sclerosis (SSc). METHODS: In total, 2,670 SSc patients and 3,245 healthy individuals from four European populations (Spain, Germany, The Netherlands, and Italy) were included in the study. Five single-nucleotide polymorphisms (SNPs) of...
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