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Article

Genomic and genetic studies of systemic sclerosis: A systematic review.

Human immunology - 1 Feb 2017

Chairta Paraskevi, Nicolaou Paschalis, Christodoulou Kyproula

Abstract excerpt

Systemic sclerosis is an autoimmune rheumatic disease characterised by fibrosis, vasculopathy and inflammation. The exact aetiology of SSc remains unknown but evidences show that various genetic factors may be involved. This review aimed to assess HLA alleles/non-HLA polymorphisms, microsatellites and chromosomal abnormalities that have thus far been associated with SSc. PubMed, Embase and Scopus databases were...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Identifiers

PMID: 27984087
DOI: 10.1016/j.humimm.2016.10.017

Genes

STAT4
IFNG
NFKB1
PRL

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