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Article

Association of CD40 polymorphisms and haplotype with risk of systemic lupus erythematosus.

Rheumatology international - 1 Jan 2016

Wu Cheng-Jiang, Guo Jing, Luo Hong-Cheng, Wei Chuan-Dong, Wang Chun-Fang, Lan Yan, Wei Ye-Sheng

Abstract excerpt

Systemic lupus erythematosus (SLE) is a prototypic autoimmune disease that is caused by genetic and environmental factors. Current evidence shows that the CD40-CD40L system plays a crucial role in the development, progression and outcome of SLE. CD40, which stimulates lymphocyte proliferation and differentiation, is an important immunomodulator and is expressed in the thyroid follicular cells as well as...

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PMID: 26289938
DOI: 10.1007/s00296-015-3345-7

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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