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Article

Association of polymorphisms in the IL1B and IL2 genes with susceptibility and severity of systemic sclerosis.

The Journal of rheumatology - 1 May 2007

Mattuzzi Silvia, Barbi Stefano, Carletto Antonio, Ravagnani Viviana, Moore Patrick S, Bambara Lisa Maria, Scarpa Aldo

Abstract excerpt

OBJECTIVE: To investigate possible associations of 9 single-nucleotide polymorphisms in the IL10, IL1B, IL1A, IL1RN, IL2, LTA, and IL6 genes with susceptibility to systemic sclerosis (SSc), and with clinical subtype of SSc patients. METHODS: A total of 78 patients with SSc [diffuse SSc (dcSSc), n = 31; limited SSc, (lcSSc), n = 47] and 692 healthy blood donors were genotyped for the following polymorphisms: IL10...

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PMID: 17444587

Genes

LTA

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