A multicenter study confirms CD226 gene association with systemic sclerosis-related pulmonary fibrosis.

doi:10.1186/ar3809

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Article

A multicenter study confirms CD226 gene association with systemic sclerosis-related pulmonary fibrosis.

Arthritis research & therapy - 24 Apr 2012

Bossini-Castillo Lara, Simeon Carmen P, Beretta Lorenzo, Broen Jasper C, Vonk Madelon C, Ríos-Fernández Raquel, Espinosa Gerard, Carreira Patricia, Camps María T, Castillo Maria J, González-Gay Miguel A, Beltrán Emma, Carmen Freire María del, Narváez Javier, Tolosa Carlos, Witte Torsten, Kreuter Alexander, Schuerwegh Annemie J, Hoffmann-Vold Anna-Maria, Hesselstrand Roger, Lunardi Claudio, van Laar Jacob M, Chee Meng May, Herrick Ariane, Koeleman Bobby Pc, Denton Christopher P, Fonseca Carmen, Radstake Timothy Rdj, Martin Javier

Abstract excerpt

INTRODUCTION: CD226 genetic variants have been associated with a number of autoimmune diseases and recently with systemic sclerosis (SSc). The aim of this study was to test the influence of CD226 loci in SSc susceptibility, clinical phenotypes and autoantibody status in a large multicenter European population. METHODS: A total of seven European populations of Caucasian ancestry were included, comprising 2,131...

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Identifiers

PMID: 22531499
DOI: 10.1186/ar3809
PMCID: PMC3446459

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Source receipt: pubmed, retrieved 6 Sept 2026.

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