Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Characterization of null and hypomorphic alleles of the Drosophila l(2)dtl/cdt2 gene: Larval lethality and male fertility.

Fly - 1 Jan 2000

Sloan Roketa S, Swanson Christina I, Gavilano Lily, Smith Kristen N, Malek Pamela Y, Snow-Smith Mayronne, Duronio Robert J, Key S Catherine Silver

Abstract excerpt

The Drosophila lethal(2)denticleless (l(2)dtl) gene was originally reported as essential for embryogenesis and formation of the rows of tiny hairs on the larval ventral cuticle known as denticle belts. It is now well-established that l(2)dtl (also called cdt2) encodes a subunit of a Cullin 4-base...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Drosophila
Share to Drosophila Proteins
Share to E2F1 Transcription Factor

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to Embryonic Development

Share to Fertility

Share to Genes, Lethal

Share to Heat-Shock Proteins

Source

Identifiers

PMID: 22722696
DOI: 10.4161/fly.20247

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 4 Sept 2026. Prepared record publication-22722696-2026-09-04.2. Manifest publication-graph-cohort-2026-09-04.2.

Source receipt: PubMed via Helena Literature Corpus, retrieved 4 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Characterization of null and hypomorphic alleles of the Drosophila l(2)dtl/cdt2 gene: Larval lethality and male fertility.PMID 22722696Read ↗

L2dtl is essential for cell survival and nuclear division in early mouse embryonic development.Semantic proximity Read ↗

DTL/CDT2 is essential for both CDT1 regulation and the early G2/M checkpoint.Semantic proximity Read ↗

Generation of mice with a conditional null allele for Tbx2.Semantic proximity Read ↗

[Recovery of genomic regions affecting lawc/Trf2 expression during Drosophila melanogaster development].Semantic proximity Read ↗

Drosophila R2D2 mediates follicle formation in somatic tissues through interactions with Dicer-1.Semantic proximity Read ↗

dTrf2 is required for transcriptional and developmental responses to ecdysone during Drosophila metamorphosis.Semantic proximity Read ↗

A developmental and molecular analysis of Cdc2 mutations in Drosophila melanogaster.Semantic proximity Read ↗

MicroRNA transgene overexpression complements deficiency-based modifier screens in Drosophila.Semantic proximity Read ↗

Identifying Genetic Players in Cell Sheet Morphogenesis Using a Drosophila Deficiency Screen for Genes on Chromosome 2R Involved in Dorsal Closure.Semantic proximity Read ↗

A developmental genetic analysis of the lysine demethylase KDM2 mutations in Drosophila melanogaster.Semantic proximity Read ↗

Dullard/Ctdnep1 modulates WNT signalling activity for the formation of primordial germ cells in the mouse embryo.Semantic proximity Read ↗

Double bromodomain-containing gene Brd2 is essential for embryonic development in mouse.Semantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.