Article
MicroRNA transgene overexpression complements deficiency-based modifier screens in Drosophila.
Genetics - 1 Feb 2012
Szuplewski Sébastien, Kugler Jan-Michael, Lim Sing Fee, Verma Pushpa, Chen Ya-Wen, Cohen Stephen M
Abstract excerpt
Dosage-sensitive modifier screening is a powerful tool for linking genes to biological processes. Use of chromosomal deletions permits sampling the effects of removing groups of genes related by position on the chromosome. Here, we explore the use of inducible microRNA transgenes as a complement...
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