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Article

dTrf2 is required for transcriptional and developmental responses to ecdysone during Drosophila metamorphosis.

Developmental dynamics : an official publication of the American Association of Anatomists - 1 Nov 2007

Bashirullah Arash, Lam Geanette, Yin Viravuth P, Thummel Carl S

Abstract excerpt

The TATA box-binding protein (TBP) related factor 2 (TRF2) has been well characterized at a biochemical level and in cultured cells. Relatively little, however, is known about how TRF2 functions in specific biological pathways during development. Here, we show that Drosophila TRF2 (dTRF2) plays an essential role in responses to the steroid hormone ecdysone during the onset of metamorphosis. Hypomorphic dTrf2...

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Methodology Data sources Editorial policy Privacy Delete account & data About Contact Helena Bioinformatics

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Source

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Identifiers

PMID: 17948312
DOI: 10.1002/dvdy.21350
PMCID: PMC2254334

Genes

TBP

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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dTrf2 is required for transcriptional and developmental responses to ecdysone during Drosophila metamorphosis.PMID 17948312Read ↗

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