Article
A developmental and molecular analysis of Cdc2 mutations in Drosophila melanogaster.
Genome - 1 Aug 1993
Clegg N J, Whitehead I P, Williams J A, Spiegelman G B, Grigliatti T A
Abstract excerpt
In fission yeast, the product of the cdc2 gene is required both for entry into S phase and mitosis. Homologs of cdc2 have been isolated from a number of metazoans, but in general they have not been amenable to genetic analysis. Here we describe P element transposon tagging of Cdc2 in Drosophila melanogaster and the analysis of 10 Cdc2 mutants. The recessive lethality of Cdc2P is associated with a P element...
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