Article
Drosophila R2D2 mediates follicle formation in somatic tissues through interactions with Dicer-1.
Mechanisms of development - 1 Jan 2000
Kalidas Savitha, Sanders Charcacia, Ye Xuecheng, Strauss Tamara, Kuhn Mary, Liu Qinghua, Smith Dean P
Abstract excerpt
The miRNA pathway has been shown to regulate developmentally important genes. Dicer-1 is required to cleave endogenously encoded microRNA (miRNA) precursors into mature miRNAs that regulate endogenous gene expression. RNA interference (RNAi) is a gene silencing mechanism triggered by double-stran...
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