Article
Identifying Genetic Players in Cell Sheet Morphogenesis Using a Drosophila Deficiency Screen for Genes on Chromosome 2R Involved in Dorsal Closure.
G3 (Bethesda, Md.) - 2 Jul 2018
Mortensen Richard D, Moore Regan P, Fogerson Stephanie M, Chiou Hellen Y, Obinero Chimdindu V, Prabhu Neel K, Wei Angela H, Crawford Janice M, Kiehart Daniel P
Abstract excerpt
Cell sheet morphogenesis characterizes key developmental transitions and homeostasis, in vertebrates and throughout phylogeny, including gastrulation, neural tube formation and wound healing. Dorsal closure, a process during Drosophila embryogenesis, has emerged as a model for cell sheet morphogenesis. ∼140 genes are currently known to affect dorsal closure and new genes are identified each year. Many of these...
Read the complete abstract on PubMedTopics
Share this publication in a Topic to start or enrich a Post.