DQw7 and the C4B null allele in rheumatoid arthritis and Felty's syndrome.

doi:10.1136/ard.49.12.976

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Article

DQw7 and the C4B null allele in rheumatoid arthritis and Felty's syndrome.

Annals of the rheumatic diseases - 1 Dec 1990

Clarkson R, Bate A S, Grennan D M, Chattopadhyay C, Sanders P, Davis M, Kelly C

Abstract excerpt

DQ beta and C4 null alleles have been defined in patients with rheumatoid arthritis, Felty's syndrome, and in control subjects. Comparison of DR4 positive subjects shows that rheumatoid disease without extra-articular features has no preferential associations with either DQ beta or C4 null varian...

Topics

Alleles
Arthritis, Rheumatoid
Complement C4b
Felty Syndrome
Genetic Markers
HLA-DQ Antigens
HLA-DR4 Antigen
Haplotypes
Humans
Linkage Disequilibrium

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