Article
The importance of C4A null genes in Norwegian patients with systemic lupus erythematosus.
Scandinavian journal of immunology - 1 Nov 1995
Skarsvåg S
Abstract excerpt
C4A null genes were determined by RFLP (Taq I) and SSO-probing on PCR-amplified C4-DNA in 51 Scandinavian patients with systemic lupus erythematosus (SLE) and 124 controls. Associations of the alleles DRB1*0301, DQA1*0501, DQB1*0201 had previously been found in this SLE group, as well as increased frequency of HLA-DRB1 and -DQ homozygosity. The frequency of the allele C4A*Q0 was increased among the patients (RR =...
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