Article
Lack of association between DQ A and DX A polymorphisms with rheumatoid arthritis and Felty's syndrome.
Disease markers - 1 Jan 2000
Bate A S, Ollier W, Grennan D M
Abstract excerpt
DQ A and DX A RFLPs were studied in DR4-positive rheumatoid arthritis, Felty's syndrome, and in DR4-positive control subjects, and in the light of the previously documented association between Felty's syndrome and the DQ B 3.1 allele (3b RFLP). In these DR4-positive subjects there were no preferential associations between DQ A or DX A polymorphisms and rheumatoid arthritis or Felty's syndrome and no evidence for...
Topics
- Arthritis, Rheumatoid
- Felty Syndrome
- Genetic Variation
- HLA-D Antigens
- HLA-DQ Antigens
- HLA-DR4 Antigen
- Haplotypes
- Humans
- Polymorphism, Restriction Fragment Length