Article
Complement C4B null allele status confers risk for systemic lupus erythematosus in a Spanish population.
European journal of immunogenetics : official journal of the British Society for Histocompatibility and Immunogenetics - 1 Aug 1998
Naves M, Hajeer A H, Teh L S, Davies E J, Ordi-Ros J, Perez-Pemen P, Vilardel-Tarres M, Thomson W, Worthington J, Ollier W E
Abstract excerpt
Genetic susceptibility to systemic lupus erythematosus (SLE) may vary amongst different populations. In UK patients, genes encoded in the HLA class II (DQA*0501/DRB1*0301) and class III [C4A*Q0 and tumour necrosis factor (TNF) polymorphisms] subregions appear to contribute to disease susceptibili...
Topics
- Alleles
- Case-Control Studies
- Complement C4b
- Female
- Gene Frequency
- Genetic Predisposition to Disease
- HLA-DR Antigens
- HLA-DRB1 Chains
- Humans
- Lupus Erythematosus, Systemic
- Male
- Microsatellite Repeats
- Polymorphism, Genetic
- Risk Factors