C4 null genes in American whites and blacks with myositis.

Article

C4 null genes in American whites and blacks with myositis.

The Journal of rheumatology - 1 Mar 1990

Moulds J M, Rolih C, Goldstein R, Whittington K F, Warner N B, Targoff I N, Reichlin M, Arnett F C

Abstract excerpt

The frequencies of C4A and C4B alleles were determined in 66 adults with myositis in relation to HLA class I and II. In whites with myositis, the C4A*Q0 allele occurred in 13/31 (47%) as compared to 25/101 (25%) normal controls (p = 0.08, relative risk = 2.7). Only 11/35 (31%) of black patients w...

Topics

Alleles
Black People
Chromosome Deletion
Complement C4
Dermatomyositis
Genes
HLA Antigens
Humans
Myositis
Phenotype
United States
White People
Black or African American

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