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Article

Association between interleukin 6 gene haplotype and Alzheimer's disease: a Brazilian case-control study.

Journal of Alzheimer's disease : JAD - 1 Jan 2013

Rasmussen Lucas, Delabio Roger, Horiguchi Lie, Mizumoto Igor, Terazaki Carlos-Renato, Mazzotti Diego, Bertolucci Paulo-Henrique, Pinhel Marcela-Augusta, Souza Dorotéia, Krieger Henrique, Kawamata Carlos, Minett Thais, Smith Marilia Cardoso, Payão Spencer-Luiz

Abstract excerpt

Alzheimer's disease (AD) is a progressive neurodegenerative disease that takes the form of a local overexpression of cytokines and other inflammatory molecules. We investigated three single-nucleotide polymorphisms (SNP) of the interleukin 6 gene (IL-6) promoter region [-174G/C (rs 1800795), -572C/G (rs 1800796), and -597G/A (rs 1800797)] in 200 patients with late-onset AD and 165 elderly controls in a Brazilian...

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PMID: 23666170
DOI: 10.3233/JAD-122407

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APOE

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