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Article

Association of IL6 Gene Polymorphisms and Neurological Disorders: Insights from Integrated Bioinformatics and Meta-Analysis.

Neuromolecular medicine - 15 Jan 2025

Harun-Or-Roshid Md, Nurul Haque Mollah Md, Jesmin

Abstract excerpt

Interleukin 6 (IL6) is an inflammatory biomarker linked to central and peripheral nervous system diseases. This study combined bioinformatics and statistical meta-analysis to explore potential associations between IL6 gene variants (rs1800795, rs1800796, and rs1800797) and neurological disorders (NDs) and brain cancer. The meta-analysis was conducted on substantial case-control datasets and revealed a significant...

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Identifiers

PMID: 39812719
DOI: 10.1007/s12017-025-08831-7

Genes

IL6

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