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Article

Incorporating genotype uncertainties into the genotypic TDT for main effects and gene-environment interactions.

Genetic epidemiology - 1 Apr 2012

Taub Margaret A, Schwender Holger, Beaty Terri H, Louis Thomas A, Ruczinski Ingo

Abstract excerpt

Genotype imputation has become a standard option for researchers to expand their genotype datasets to improve signal precision and power in tests of genetic association with disease. In imputations for family-based studies however, subjects are often treated as unrelated individuals: currently, only BEAGLE allows for simultaneous imputation for trios of parents and offspring; however, only the most likely...

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Identifiers

PMID: 22678881
DOI: 10.1002/gepi.21615
PMCID: PMC3645945

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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