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Article

A simple and robust TDT-type test against genotyping error with error rates varying across families.

Human heredity - 1 Jan 2007

Cheng K F, Chen J H

Abstract excerpt

The transmission/disequilibrium test (TDT), a family based test of linkage and association, is a popular test for studies of complex inheritance, as it is nonparametric and robust against spurious conclusions induced by hidden genetic structure, such as stratification or admixture. However, the TDT may be biased by genotyping errors. Undetected genotyping errors may be contributing to an inflated type I error...

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PMID: 17476111
DOI: 10.1159/000101963

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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