Article
Using case-parent triads to estimate relative risks associated with a candidate haplotype.
Annals of human genetics - 1 May 2009
Shi Min, Umbach David M, Weinberg Clarice R
Abstract excerpt
Estimating haplotype relative risks in a family-based study is complicated by phase ambiguity and the many parameters needed to quantify relative risks for all possible diplotypes. This problem becomes manageable if a particular haplotype has been implicated previously as relevant to risk. We fit log-linear models to estimate the risks associated with a candidate haplotype relative to the aggregate of other...
Read the complete abstract on PubMedTopics
Share this publication in a Topic to start or enrich a Post.
