Article
Robust transmission/disequilibrium test for incomplete family genotypes.
Genetics - 1 Dec 2004
Sebastiani Paola, Abad Maria M, Alpargu Gülhan, Ramoni Marco F
Abstract excerpt
Several solutions have been proposed to extend the transmission disequilibrium test (TDT) to include cases with missing parental genotype. However, completion of the missing parental genotype may bias the test if the underlying missing data mechanism is informative. Furthermore, all these solutions resolve the problem of missing parental genotype, while offspring with missing genotypes are typically ignored. We...
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