Article
Lack of effects of the TNF-alpha and IL-10 gene polymorphisms in Mexican patients with lepromatous leprosy.
Leprosy review - 1 Mar 2012
Velarde Félix Jesús Salvador, Cázarez-Salazar Silvestre, Ríos-Tostado Juan José, Flores-Garcia Aurelio, Rangel-Villalobos Héctor, Murillo-Llanes Joel
Abstract excerpt
Several human genetic variants have been associated with susceptibility or resistance to leprosy. The aim of this study was to assess whether gene polymorphisms of -308 G/A TNF-alpha and -819 T/C IL-10 are associated with lepromatous leprosy in Mexican mestizos patients from northwest Mexico. We genotyped these polymorphisms by means of polymerase chain reaction (PCR) and restriction fragment length polymorphisms...
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