IL-10 gene promoter polymorphisms and leprosy in a Colombian population sample.

doi:10.1590/S0120-41572012000100009

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Article

IL-10 gene promoter polymorphisms and leprosy in a Colombian population sample.

Biomedica : revista del Instituto Nacional de Salud - 1 Jan 2000

Cardona-Castro Nora, Sánchez-Jiménez Miryam, Rojas Winston, Bedoya-Berrío Gabriel

Abstract excerpt

INTRODUCTION: Polymorphisms in promoters of genes code for cytokines that affect transcription levels. Several have been associated with leprosy patients that have functional and clinical implications. OBJECTIVE: Polymorphisms in the promoter of the IL10 gene of leprosy patients will be compared frequencies in normal population. MATERIALS AND METHODS: SNPs (single nucleotide polymorphism) -1082 A/G (rs1800896),...

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PMID: 23235789
DOI: 10.1590/S0120-41572012000100009

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