Article
Frequency distribution of interleukin-10 haplotypes (-1082 A>G, -819 C>T, and -592 C>A) in a Mexican population.
Genetics and molecular research : GMR - 3 Nov 2016
Vázquez-Villamar M, Palafox-Sánchez C A, Hernández-Bello J, Muñoz-Valle J F, Valle Y, Cruz A, Alatorre-Meza A I, Oregon-Romero E
Abstract excerpt
Interleukin 10 (IL-10) is an immunoregulatory cytokine with multiple roles in the immune system. Three single nucleotide polymorphisms at positions -1082 (A>G), -819 (C>T), and -592 (C>A) in the promoter region of the IL10 gene are believed to be associated with different inflammatory, infectious, and autoimmune diseases. These polymorphisms exhibit a strong linkage disequilibrium (LD) and form three principal...
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