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Article

Influence of TNF and IL10 gene polymorphisms in the immunopathogenesis of leprosy in the south of Brazil.

International journal of infectious diseases : IJID : official publication of the International Society for Infectious Diseases - 1 Jul 2009

Franceschi Danilo Santana Alessio, Mazini Priscila Saamara, Rudnick Cristiane Conceição Chagas, Sell Ana Maria, Tsuneto Luiza Tamie, Ribas Maria Lúcia, Peixoto Paulo Roberto, Visentainer Jeane Eliete Laguila

Abstract excerpt

OBJECTIVE: To determine whether cytokine polymorphisms are associated with leprosy and/or their subtypes in a Brazilian population. METHODS: Genotyping using polymerase chain reaction with sequence-specific primers (PCR-SSP) was performed for: TNF(-308/-238), IL2(-330/+166), IL6(-174), IFNG(+874), TGFB1(+869/+915), and IL10(-592/-819/-1082) in 240 healthy controls and 167 patients with leprosy. RESULTS: For...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Source

Identifiers

PMID: 19058987
DOI: 10.1016/j.ijid.2008.08.019

Genes

TNF
IFNG
TGFB1

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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