Association of IL10 Polymorphisms and Leprosy: A Meta-Analysis.

doi:10.1371/journal.pone.0136282

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Article

Association of IL10 Polymorphisms and Leprosy: A Meta-Analysis.

PloS one - 1 Jan 2015

Alvarado-Arnez Lucia Elena, Amaral Evaldo P, Sales-Marques Carolinne, Durães Sandra M B, Cardoso Cynthia C, Nunes Sarno Euzenir, Pacheco Antonio G, Lana Francisco C F, Moraes Milton Ozório

Abstract excerpt

Leprosy is a chronic infectious disease that depends on the interplay of several factors. Single nucleotide polymorphisms (SNPs) in host immune related genes have been consistently suggested as participants in susceptibility towards disease. Interleukin-10 (IL-10) is a crucial immunomodulatory cytokine in mycobacterial pathogenesis and especially the -819C>T SNP (rs1800871) has been tested in several case-control...

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PMID: 26340474
DOI: 10.1371/journal.pone.0136282
PMCID: PMC4560376

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