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Article

Association of polymorphisms in the TNFA, TNFRSF1A and TNFRSF1B genes with lepromatous leprosy in Western Mexican patients.

Journal of infection in developing countries - 30 May 2024

Montoya-Buelna Margarita, Alvarado-Navarro Anabell, Muñoz-Valle Jose F, Lopez-Roa Rocio I, Guerrero-Velazquez Celia, Fafutis-Morris Mary

Abstract excerpt

INTRODUCTION: Studies in different populations have shown that single-nucleotide polymorphisms (SNPs) of tumor necrosis factor-alpha (TNFα) and TNF receptors 1 and 2 (TNFR1 and TNFR2) may be involved in the pathogenesis of lepromatous leprosy (LL). To further explore the results in a Mexican population, we compared the frequencies of the polymorphisms in - 308 G>A TNFA (rs1800629), - 383 A>C TNFRS1A (rs2234649),...

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PMID: 38865403
DOI: 10.3855/jidc.17658

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