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Article

Estrogen synthesis genes CYP19A1, HSD3B1, and HSD3B2 in hypertensive disorders of pregnancy.

Endocrine - 1 Dec 2012

Shimodaira Masanori, Nakayama Tomohiro, Sato Ichiro, Sato Naoyuki, Izawa Noriko, Mizutani Yoshihiro, Furuya Kiyohide, Yamamoto Tatsuo

Abstract excerpt

Hypertension in pregnancy is a multifactorial disorder caused by a complex combination of environmental factors and several predisposing genes. Since estrogen modulates placental vascular development, estrogen synthases are considered plausible candidate genes. The aim of this haplotype-based case-control study was to estimate whether polymorphisms of the maternal estrogen synthesis genes (CYP19A1, HSD3B1 and...

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PMID: 22638611
DOI: 10.1007/s12020-012-9699-7

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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